Document and Entity Information Document Type Document Quarterly Report Document Transition Report Document Period End Date Entity File Number Entity Registrant Name Entity Incorporation, State or Country Code Entity Tax Identification Number Entity Address, Address Line One Entity Address, Address Line Two Entity Address, City or Town Entity Address, State or Province Entity Address, Postal Zip Code City Area Code Local Phone Number Title of 12(b) Security Trading Symbol Security Exchange Name Entity Current Reporting Status Entity Interactive Data Current Entity Filer Category Entity Small Business Entity Emerging Growth Company Entity Shell Company Entity Common Stock, Shares Outstanding Entity Central Index Key Current Fiscal Year End Date Document Fiscal Year Focus Document Fiscal Period Focus Amendment Flag CONDENSED CONSOLIDATED BALANCE SHEETS Statement [Table] Statement [Line Items] Assets [Abstract] ASSETS Assets, Current [Abstract] CURRENT ASSETS: Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents Carrying value of deposits held with banks for short period, usually less than one year or the normal operating cycle, whichever is longer. Short-term Bank Deposits Short-term bank deposits Accounts Receivable, Net, Current Accounts receivable - Trade Other Assets, Current Other assets Inventory, Net Inventories Total inventory Assets, Current Total current assets Assets, Noncurrent [Abstract] NON-CURRENT ASSETS: Assets for Plan Benefits, Defined Benefit Plan Funds in respect of employee rights upon retirement Property, Plant and Equipment, Net Property and equipment, net Deferred Income Tax Assets, Net Deferred income tax asset Operating Lease, Right-of-Use Asset Operating lease right of use assets Assets Total assets Liabilities and Equity [Abstract] LIABILITIES AND STOCKHOLDERS' EQUITY Liabilities, Current [Abstract] CURRENT LIABILITIES: Accounts Payable and Accrued Liabilities, Current [Abstract] Accounts payable and accruals: Accounts payable and accruals - other: Accounts Payable, Trade, Current Trade Accounts Payable, Other, Current Other Operating Lease, Liability, Current Operating lease liabilities Contract with Customer, Liability, Current Contracts liability Convertible Debt, Current Aggregate principal amount Convertible notes Liabilities, Current Total current liabilities Liabilities, Noncurrent [Abstract] LONG TERM LIABILITIES: Liability, Pension and Other Postretirement and Postemployment Benefits, Noncurrent Liability for employee rights upon retirement Operating Lease, Liability, Noncurrent Operating lease liabilities Liabilities, Noncurrent Total long term liabilities Liabilities Total liabilities Commitments and Contingencies COMMITMENTS Stockholders' Equity Attributable to Parent Ending balance Beginning balance STOCKHOLDERS' EQUITY Liabilities and Equity Total liabilities and stockholders' equity CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS Product and Service [Axis] Product and Service [Domain] Goods License and R&D Services Revenues. TOTAL REVENUE Revenues Cost of Revenue COST OF GOODS SOLD Research and Development Expense RESEARCH AND DEVELOPMENT EXPENSES Selling, General and Administrative Expense SELLING, GENERAL AND ADMINISTRATIVE EXPENSES Operating Income (Loss) OPERATING LOSS Other Nonoperating Expense FINANCIAL EXPENSES Financial expense Other Nonoperating Income FINANCIAL INCOME Nonoperating Income (Expense) FINANCIAL INCOME (EXPENSES), NET Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest LOSS BEFORE TAX BENEFIT (TAXES ON INCOME) Income Tax Expense (Benefit) TAX BENEFIT (TAXES ON INCOME) Total taxes on income (tax benefit) NET LOSS FOR THE PERIOD Earnings Per Share, Basic LOSS PER SHARE OF COMMON STOCK - BASIC Earnings Per Share, Diluted LOSS PER SHARE OF COMMON STOCK - DILUTED Weighted Average Number of Shares Outstanding, Basic WEIGHTED AVERAGE NUMBER OF SHARES OF COMMON STOCK USED IN COMPUTING LOSS PER SHARE- BASIC Weighted Average Number of Shares Outstanding, Diluted WEIGHTED AVERAGE NUMBER OF SHARES OF COMMON STOCK USED IN COMPUTING LOSS PER SHARE- DILUTED CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY (CAPITAL DEFICIENCY) Equity Components [Axis] Equity Component [Domain] Common Stock Additional Paid-in Capital Accumulated Deficit Adjustments for New Accounting Pronouncements [Axis] Type of Adoption [Domain] Accounting Standards Update 2020-06 [Member] ASU 2020-06 Cumulative Effect, Period of Adoption [Axis] Cumulative Effect, Period of Adoption [Domain] Cumulative Effect, Period of Adoption, Adjustment [Member] Adjustment Effect of Change Shares, Outstanding Ending balance (in shares) Beginning balance (in shares) Stock Issued During Period, Value, New Issues Issuance of common stock, net of issuance cost Stock Issued During Period, Shares, New Issues Issuance of common stock, net of issuance cost (in shares) Number of shares issued (in shares) Equity impact of the value of new stock issued during the period. Includes shares issued in a sales agreement. Stock Issued During Period, Value, Sales Agreement Issuance of common stock under the Sales Agreement, net Stock Issued During Period, Shares, Sales Agreement Stock Issued During Period, Shares, Sales Agreement Issuance of common stock under the Sales Agreement, net (in shares) Adjustments to Additional Paid in Capital, Share-based Compensation, Requisite Service Period Recognition Share-based compensation related to stock options Amount of recognized equity-based compensation during the period for restricted stock awards. Share Based Compensation Restricted Stock Awards Net Of Forfeitures Share-based compensation related to restricted stock awards Share Based Compensation Restricted Stock Awards Net Of Forfeitures Shares Share Based Compensation Restricted Stock Awards Net Of Forfeitures Shares Share-based compensation related to restricted stock awards (in shares) Common Stock, Par or Stated Value Per Share Common Stock, Shares Authorized CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS Net Cash Provided by (Used in) Operating Activities [Abstract] CASH FLOWS FROM OPERATING ACTIVITIES: Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net loss Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments required to reconcile net loss to net cash provided by (used in) operating activities: Share-based Compensation Share-based compensation Depreciation Depreciation Foreign Currency Transaction Gain (Loss), Unrealized Financial income, net Pension and Other Postretirement Benefits Cost (Reversal of Cost) Changes in accrued liability for employee rights upon retirement Deferred Income Tax Expense (Benefit) Changes in deferred tax asset Deferred taxes on income Gain (loss) on amounts funded in respect of employee rights upon retirement. Gain Loss On Amounts Funded In Respect Of Employee Rights Upon Retirement Loss (gain) on amounts funded in respect of employee rights upon retirement Amortization of Debt Issuance Costs and Discounts Amortization of debt issuance costs and debt discount Increase (Decrease) in Operating Capital [Abstract] Changes in operating assets and liabilities: Increase (Decrease) in Contract with Customer, Liability Increase (decrease) in contracts liability Increase (Decrease) in Accounts Receivable Decrease in accounts receivable-trade and other assets Amount of Net Change in Operating Lease Right Of use Assets. Change in Operating Lease Right Of use Assets Changes in operating lease right of use assets, net Increase (Decrease) in Inventories Increase in inventories Increase (Decrease) in Accounts Payable and Accrued Liabilities Increase (decrease) in accounts payable and accruals Net Cash Provided by (Used in) Operating Activities Net cash provided by (used in) operating activities Net Cash Provided by (Used in) Investing Activities [Abstract] CASH FLOWS FROM INVESTING ACTIVITIES: Amount of cash inflow from sale of short-term deposits. Proceeds from Sale of Short-term Deposits Proceeds from sale of short-term deposits Payments to Acquire Property, Plant, and Equipment Purchase of property and equipment Payments for (Proceeds from) Other Investing Activities Amounts funded in respect of employee rights upon retirement, net Net Cash Provided by (Used in) Investing Activities Net cash provided by (used in) investing activities CASH FLOWS FROM FINANCING ACTIVITIES: Proceeds from Issuance of Common Stock Proceeds from issuance of common stock under the Sales Agreement, net Stock issuance proceeds Net Cash Provided by (Used in) Financing Activities Net cash provided by financing activities Effect of Exchange Rate on Cash and Cash Equivalents EFFECT OF EXCHANGE RATE CHANGES ON CASH AND CASH EQUIVALENTS Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect NET INCREASE IN CASH AND CASH EQUIVALENTS Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents BALANCE OF CASH AND CASH EQUIVALENTS AT END OF PERIOD BALANCE OF CASH AND CASH EQUIVALENTS AT BEGINNING OF PERIOD Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] SUPPLEMENTARY INFORMATION ON INVESTING AND FINANCING ACTIVITIES NOT INVOLVING CASH FLOWS: Capital Expenditures Incurred but Not yet Paid Purchase of property and equipment Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Operating lease right of use assets obtained in exchange for new operating lease liabilities Supplemental Cash Flow Information [Abstract] SUPPLEMENTARY DISCLOSURE ON CASH FLOWS Interest Paid, Excluding Capitalized Interest, Operating Activities Interest paid Amount of cash received for interest. Interest Received, Net Interest received SIGNIFICANT ACCOUNTING POLICIES Basis of Presentation and Significant Accounting Policies [Text Block] SIGNIFICANT ACCOUNTING POLICIES INVENTORIES Inventory Disclosure [Text Block] INVENTORIES FAIR VALUE MEASUREMENT Fair Value Disclosures [Text Block] FAIR VALUE MEASUREMENT REVENUES The entire disclosure pertaining to revenue. Revenue Disclosure [Text Block] REVENUES STOCK TRANSACTIONS Stockholders' Equity Note Disclosure [Text Block] STOCK TRANSACTIONS TAXES ON INCOME Income Tax Disclosure [Text Block] TAXES ON INCOME SUPPLEMENTARY FINANCIAL STATEMENT INFORMATION Additional Financial Information Disclosure [Text Block] SUPPLEMENTARY FINANCIAL STATEMENT INFORMATION SUBSEQUENT EVENTS Subsequent Events [Text Block] SUBSEQUENT EVENTS Nature Of Operations Policy Nature Of Operations [Policy Text Block] General Basis of Accounting, Policy [Policy Text Block] Basis of presentation Earnings Per Share, Policy [Policy Text Block] Loss per share Debt, Policy [Policy Text Block] Convertible notes New Accounting Pronouncements, Policy [Policy Text Block] New accounting pronouncements Accounting Standards Update and Change in Accounting Principle [Table Text Block] Schedule of ASU 2020-06 on the condensed consolidated balance sheet Schedule of Inventory, Current [Table Text Block] Schedule of Inventory Debt Instrument [Axis] Debt Instrument, Name [Domain] Represents the information pertaining to seven point five percentage senior secured convertible notes due 2024. 2024 Notes Fair Value Measurement Inputs and Valuation Techniques [Table Text Block] Schedule of Fair Value Assumptions Disaggregation of Revenue [Table Text Block] Schedule of Company's Disaggregation of Revenues Schedule of Components of Income Tax Expense (Benefit) [Table Text Block] Schedule of Components of Income Tax Expense (Benefit) The tabular disclosure for supplemental balance sheets information. Supplementary Balance Sheets Information [Table Text Block] Supplemental Information, Balance Sheets Significant Accounting Policies [Table]. Significant Accounting Policies [Table] Type of Arrangement and Non-arrangement Transactions [Axis] Arrangements and Non-arrangement Transactions [Domain] Amended Pfizer Agreement [Member] Amended Pfizer Agreement Chiesi Agreements [Member] Chiesi Agreements Chiesi US Agreement Chiesi Ex-US Agreement n/a Chiesi US Agreement and Chiesi Ex-US Agreement Fill/Finish Agreement [Member] Fill/Finish Agreement Legal Entity [Axis] Entity [Domain] Protalix Bio Therapeutics Incorporation [Member]. Protalix Bio Therapeutics Incorporation Geographical [Axis] Geographical [Domain] Brazil Range [Axis] Range [Domain] Minimum Maximum Represents information pertaining to convertible notes due 2021 and 2024. Notes 2021 and 2024 Sale of Stock [Axis] Sale of Stock [Domain] Represents the information pertaining to At The Market equity offering. ATM Shares Significant Accounting Policies [Line Items] Represents the number of global licensing and supply agreements. Number Of Global Licensing And Supply Agreements Number of global licensing and supply agreements The amount of upfront, non refundable and non creditable payment receivable under the agreement for licensing rights. Upfront Nonrefundable Non creditable Payment Receivable Non-refundable payment receivable Sale of stock, maximum offering price. Sale Of Stock Maximum Offering Price Sale of stock, maximum offering price The maximum amount payable to the entity to cover development costs under agreement. Additional Amounts Payable To Cover Development Costs Additional amounts payable to cover development costs Extended term of agreement. Extended Term Of Agreement Extended term of agreement Agreement Amendment Payment Receivable Agreement Amendment Payment Receivable Agreement amendment payment receivable Change In Amount Receivable For Achievement Of Regulatory And Commercial Milestones Change In Amount Receivable For Achievement Of Regulatory And Commercial Milestones Change in amount receivable for achievement of regulatory and commercial milestones The total amount payable to entity for the achievement of regulatory and commercial milestones. Additional Amount Payable For Achievement Of Regulatory And Commercial Milestones Additional amount payable for achievement of regulatory and commercial milestones Amount of milestone payment received upon achievement of certain milestone. Milestone Payment Received Amount of milestone payment received Represents the payment as a percentage of future net sales. Payment On Net Sales Percentage Payment on net sales percentage Collaborative arrangement revenues and expense sharing percentage. Collaborative Arrangement Revenues Expenses Sharing Percentage Collaborative arrangement revenues and expenses sharing percentage Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Antidilutive securities excluded from computation of earnings per share, amount Retained Earnings (Accumulated Deficit) Accumulated deficit Debt Instrument, Interest Rate, Stated Percentage Interest rate (as a percent) Minimum cash balance required to be maintained under long term debt agreements. Maintain of Minimum Cash Balance Minimum cash balance required Cumulative Effect, Period of Adoption, Adjusted Balance Represents the information pertaining to balances without adoption of ASU 2020-06. Balances Without Adoption of ASU 2020-06 [Member] Balances without Adoption of ASU 2020-06 Additional Paid in Capital, Common Stock Additional paid in capital Inventory, Raw Materials, Net of Reserves Raw materials Inventory, Work in Process, Net of Reserves Work in progress Inventory, Finished Goods, Net of Reserves Finished goods Fair Value Measurement Inputs and Valuation Techniques [Table] Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Domain] Level 3 Measurement Input Type [Axis] Measurement Input Type [Domain] Share Price. Stock price Expected term Risk free rate Volatility Yield Yield Debt Instrument, Measurement Input Measurement input Long-term Debt, Gross Debt instrument carrying amount Convertible Debt, Fair Value Disclosures Debt instrument fair value Global except for Brazil Pfizer Schedule of Stock by Class [Table] Plan Name [Axis] Plan Name [Domain] It represent the employee stock incentive plan for the particular period. 2006 Employee Stock Incentive Plan Restricted Stock Shares of restricted Common Stock Class of Stock [Line Items] Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period Number of shares granted Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period Vesting period Represents the vesting of awards in number of quarterly increments. Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting, Number of Quarterly Increments Vesting in number of quarterly increments Share based compensation arrangement by share based payment award grant date fair value. Share Based Compensation Arrangement By Share Based Payment Award Grant Date Fair Value Grant Date Fair Value Current Income Tax Expense (Benefit) Current taxes on income Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent Statutory income tax rate Effective Income Tax Rate Reconciliation, Percent Effective income tax rate (as a percent) Employee-related Liabilities, Current Payroll and related expenses Interest Payable, Current Interest Payable Accrued Vacation, Current Provision for vacation Accrued Liabilities, Current Accrued expenses Accrued Royalties, Current Royalties payable Taxes Payable, Current Income tax payable Carrying value as of the balance sheet date of reserve for deductions from revenue. Reserve For Deductions From Revenue Current Sales reserve Carrying value as of the balance sheet date of obligations incurred and payable to property and equipment suppliers. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Accounts Payable, Property And Equipment Suppliers, Current Property and equipment suppliers Accounts Payable, Current Accounts payable and accruals - other Subsequent Event [Table] Subsequent Event Type [Axis] Subsequent Event Type [Domain] Subsequent Event Represents information pertaining to supply and technology transfer agreement with Fiocruz. Brazil Agreement with Fiocruz Title of Individual [Axis] Relationship to Entity [Domain] Chief Executive Officer Subsequent Event [Line Items] Proceeds from Customers Total proceeds from sale of products