SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, DC 20549

                                   FORM 12b-25

                           NOTIFICATION OF LATE FILING

                                                  Commission File No.  000-27836

(Check one)

[ ] Form 10-K and Form 10-KSB     [ ] Form 11-K

[ ] Form 20-F     [X] Form 10-Q and Form 10-QSB     [ ] Form N-SAR

For period ended:  March 31, 2001

[ ] Transition Report on Form 10-K and Form 10-KSB

[ ] Transition Report on Form 20-F

[ ] Transition Report on Form 11-K

[ ] Transition Report on Form 10-Q and Form 10-QSB

[ ] Transition Report on Form N-SAR

For the transition period ended

Read Attached Instruction Sheet before Preparing Form. Please Print or Type.

     Nothing in this form shall be construed to imply that the Commission has
verified any information contained herein.

     If the notification relates to a portion of the filing checked above,
identify the item(s) to which the notification relates:_________________________
________________________________________________________________________________

                                     PART I
                             REGISTRANT INFORMATION

     Full name of registrant:   Orthodontix, Inc.

     Former name if applicable__________________________________________________
________________________________________________________________________________

     Address of principal executive office (Street and number): 1428 Brickell
Avenue, Suite 105

     City, state and zip code:  Miami, Florida  33131

PART II RULE 12b-25(b) AND (c) If the subject report could not be filed without unreasonable effort or expense and the registrant seeks relief pursuant to Rule 12b-25(b), the following should be completed. (Check box if appropriate.) (a) The reasons described in reasonable detail in Part III of this form could not be eliminated without unreasonable effort or expense; (b) [X] The subject annual report, semi-annual report, transition report on Form 10-K, 10-KSB, 20-F, 11-K or Form N-SAR, or portion thereof will be filed on or before the 15th calendar day following the prescribed due date; or the subject quarterly report or transition report on Form 10-Q, 10-QSB, or portion thereof will be filed on or before the fifth calendar day following the prescribed due date; and (c) The accountant's statement or other exhibit required by Rule 12b-25(c) has been attached if applicable. PART III NARRATIVE State below in reasonable detail the reasons why Form 10-K, 10-KSB, 11-K, 20-F, 10-Q, 10-QSB, N-SAR or the transition report portion thereof could not be filed within the prescribed time period. (Attach extra sheets if needed.) Registrant is finalizing an agreement to terminate its affiliation with an orthodontic practice owned by the chief executive officer of the Registrant, the terms of which will be significant to the subject report. PART IV OTHER INFORMATION (1) Name and telephone number of person to contact in regard to this notification. Judith Kenney, Montello & Kenney, P.A. (305) 373-0300 - -------------------------------------------------------------------------------- (Name) (Area Code) (Telephone Number) (2) Have all other periodic reports required under Section 13 or 15(d) of the Securities Exchange Act of 1934 or Section 30 of the Investment Company Act of 1940 during the preceding 12 months or for such shorter period that the registrant was required to file such report(s) been filed? If the answer is no, identify report(s). Yes [X] No [ ] (3) Is it anticipated that any significant change in results of operations from the corresponding period for the last fiscal year will be reflected by the earnings statements to be included in the subject report or portion thereof? Yes [ ] No [X] If so: attach an explanation of the anticipated change, both narratively and quantitatively, and, if appropriate, state the reasons why a reasonable estimate of the results cannot be made. - -------------------------------------------------------------------------------- (Name of Registrant as Specified in Charter)

Orthodontix, Inc. has caused this notification to be signed on its behalf by the undersigned thereunto duly authorized. Date May 15, 2001 By /s/ Glenn L. Halpryn ---------------------------------------- Glenn L. Halpryn, Chairman and President 12b-25-3