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SEC FORM 4 SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940 		 
OMB APPROVAL
OMB Number: 3235-0287
Estimated average burden
hours per response: 0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person*
FROST PHILLIP MD ET AL
(Last) (First) (Middle)
4400 BISCAYNE BLVD
(Street)
MIAMI FL 33137-3227
(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
ORTHODONTIX INC [ ORTX.OB ] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
X Director X 10% Owner
Officer (give title below) Other (specify below)
3. Date of Earliest Transaction (Month/Day/Year)
01/31/2007
4. If Amendment, Date of Original Filed (Month/Day/Year)
 6. Individual or Joint/Group Filing (Check Applicable Line)
Form filed by One Reporting Person
X Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock(1) 01/31/2007 X 2,157,302 A $1.376 9,766,273 I Frost Gamma Investments Trust(2)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Warrants(1) $1.376 01/31/2007 X 2,157,302 12/31/2006 01/31/2007 Common Stock 2,157,302 (3) 0 I Frost Gamma Investments Trust(2)
1. Name and Address of Reporting Person*
FROST PHILLIP MD ET AL
(Last) (First) (Middle)
4400 BISCAYNE BLVD
(Street)
MIAMI FL 33137-3227
(City) (State) (Zip)
1. Name and Address of Reporting Person*
Frost Gamma Investment Trust
(Last) (First) (Middle)
4400 BISCAYNE BOULEVARD
15TH FLOOR
(Street)
MIAMI FL 33137
(City) (State) (Zip)
Explanation of Responses:
1. The share amounts reflect the Reporting Person's holdings after a 1:10 reverse stock split, which was effective in December 2006.
2. These securities are held by Frost Gamma Investments Trust, of which the reporting person is the trustee. Frost Gamma Limited Partnership is the sole and exclusive beneficiary of Frost Gamma Investments Trust. The Reporting Person is one of two limited partners of Frost Gamma, L.P. The general partner of Frost Gamma, L.P. is Frost Gamma, Inc., and the sole shareholder of Frost Gamma, Inc. is Frost-Nevada Corporation. The Reporting Person is also the sole shareholder of Frost-Nevada Corporation.
3. Received in exchange for warrants to purchase 32,111 ordinary shares of Protalix Ltd. in connection with the merger of Protalix Acquisition Co. Ltd., a wholly-owned subsidiary of the Company, with and into Protalix Ltd. and the resulting acquisition of Protalix Ltd. by the Company.
/s/ Phillip Frost, M.D. 02/02/2007
/s/ Phillip Frost, M.D. as Trustee 02/02/2007
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
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Exhibit 99
Form 4 - Joint Filer Information

Name:                                Frost Gamma Investments Trust
Address:                                4400 Biscayne Boulevard
                                15th Floor
                                Miami, Florida  33137
Designated Filer:            &nbs
p;           Steven D. Rubin
Issuer & Ticker Symbol:                Orthodontix, Inc. (ORTX.OB)
Date of Event Requiring
        Statement:                January 31, 2007
Signature:

/s/ Phillip Frost, M.D., Trustee
Phillip Frost, M.D., Trustee

Signature:

/s/ Phillip Frost, M.D
Phillip Frost, M.D.